Captain Seamus Coleman has been dominated out of the Republic of Eire’s Nations League fixtures with Finland and England.
Norwich Metropolis defender Shane Duffy and Celtic ahead Adam Idah have additionally withdrawn from Heimir Hallgrímsson’s squad.
Wolves’ Matt Doherty has been recalled as cowl whereas Everton’s Jake O’Brien and Southampton’s Ryan Manning are additionally drafted in.
The Republic host Finland on Thursday and tackle England at Wembley of their closing Nations League fixture on Sunday, 17 November.
Coleman sustained a foot damage whereas taking part in for the Republic of Eire in September’s Nations League opener with England in Dublin.
The 36-year-old returned to the Everton bench in the midst of October however has not featured for Sean Dyche’s facet.
Having initially been referred to as into the Irish squad, he has now been changed by Doherty, who has been out of favour underneath new supervisor Hallgrimsson.
Southampton’s Manning is one other full-back possibility whereas Everton centre again O’Brien has been referred to as in as cowl for Duffy.
The Irish are third behind Greece and England in League B Group 2 after 4 matches, with their sole victory coming away to backside facet Finland.